Selenium Sulfide
seh-LEE-nee-um SUL-fide
What Is Selenium Sulfide?
An antifungal agent used in medicated shampoos to treat dandruff and seborrheic dermatitis. It works by slowing the growth of skin cells on the scalp and killing fungi.
Source: Synthetic mineral compound
Origin: Synthetic
Also known as: Selenium Disulfide
What Does Selenium Sulfide Do to Your Hair?
Reduces scalp cell turnover rate and kills Malassezia fungi to control dandruff and seborrheic dermatitis. Also helps reduce excess scalp oiliness. Typically used as a treatment rather than daily shampoo.
Best For
Severe dandruff, seborrheic dermatitis, oily scalp, tinea versicolor
Not Recommended For
Color-treated hair (will discolor), blonde hair, chemically treated hair, dry hair
Concentration Matters
1-2.5% in medicated shampoos
Hair Type Compatibility
Method Compatibility
Safety & Regulation
Effective but can be harsh. May discolor blonde, gray, or chemically treated hair. Can cause scalp irritation, dryness, and hair loss with overuse. Should not be used on broken or inflamed skin.
FDA Status: Approved
FDA approves as OTC anti-dandruff active at 1% (OTC) and 2.5% (prescription).
EWG Score: 5/10
HairAide Verdict
A strong anti-dandruff treatment best reserved for moderate to severe cases. Use with caution on colored or chemically treated hair. Not for everyday use, and always follow with a good conditioner.
Products That Contain Selenium Sulfide
Medicated anti-dandruff shampoos, prescription scalp treatments
Alternatives to Selenium Sulfide
If you want to avoid Selenium Sulfide, look for products with these ingredients instead:
Zinc Pyrithione, Ketoconazole, Piroctone Olamine
Frequently Asked Questions
Selenium Sulfide has a safety rating of 5/10. It's generally acceptable but may cause issues for some hair types. Effective but can be harsh. May discolor blonde, gray, or chemically treated hair. Can cause scalp irritation, dryness, and hair loss with overuse. Should not be used on broken or inflamed skin.
Selenium Sulfide is not CG-method approved. Curly hair types may want to avoid this ingredient or use products containing it sparingly.
No, Selenium Sulfide is not approved for the Curly Girl method.
Some alternatives to Selenium Sulfide include: Zinc Pyrithione, Ketoconazole, Piroctone Olamine
Get Our Free Ingredient Decoder Cheat Sheet
Take the guesswork out of reading product labels. Our printable cheat sheet helps you decode ingredients while you shop.
Check What's In Your Products
Use our free Hair Product Label Analyzer to check any product's ingredient list instantly.
Analyze My Product →