Gluconolactone
GLOO-koh-no-LAK-tone
What Is Gluconolactone?
A polyhydroxy acid (PHA) that provides gentle exfoliation, chelation, and antioxidant benefits. Milder than AHAs and BHAs, it is suitable for sensitive scalps and gentle scalp exfoliation.
Source: Derived from glucose by oxidation
Origin: Natural
Also known as: PHA, Glucono Delta-Lactone, GDL
What Does Gluconolactone Do to Your Hair?
Provides gentle chemical exfoliation to the scalp, removing dead skin cells and buildup without the irritation of stronger acids. Also acts as a chelating agent and humectant. Provides antioxidant protection to hair and scalp.
Best For
Sensitive scalp, dandruff-prone scalp, dry scalp, all hair types
Not Recommended For
None known
Concentration Matters
1-5% in products
Hair Type Compatibility
Method Compatibility
Safety & Regulation
Very safe and gentle. The mildest chemical exfoliant available due to its large molecular size. Suitable for sensitive skin. Also functions as a natural preservative booster. Non-irritating.
FDA Status: Generally Recognized As Safe
FDA classifies as GRAS for food. Safe for cosmetic use.
EWG Score: 1/10
HairAide Verdict
The gentlest chemical exfoliant for the scalp. If you want scalp exfoliation benefits without any irritation, gluconolactone is the answer. Also provides chelating and antioxidant bonuses.
Products That Contain Gluconolactone
Gentle scalp exfoliants, sensitive scalp treatments, clarifying products, natural preservative systems
Alternatives to Gluconolactone
If you want to avoid Gluconolactone, look for products with these ingredients instead:
Salicylic Acid, Lactic Acid, Mandelic Acid
Frequently Asked Questions
Yes, Gluconolactone has a safety rating of 9/10 and is generally considered safe for use in hair products. Very safe and gentle. The mildest chemical exfoliant available due to its large molecular size. Suitable for sensitive skin. Also functions as a natural preservative booster. Non-irritating.
Gluconolactone is CG-method approved and is generally considered safe for curly hair.
Yes, Gluconolactone is approved for the Curly Girl method.
Some alternatives to Gluconolactone include: Salicylic Acid, Lactic Acid, Mandelic Acid
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